Summer Intern - Research Early Development (RED)

Job description

·  Job facts

The Summer @ Roche Intern Program has been developed to provide students with a fun yet rewarding summer through hands-on experience and numerous opportunities to network with other interns as well as employees in the organization. Additionally, we help our students meet their career development and educational goals while potentially building a future with the Roche organization. Leveraging the education you received already, we hope to give you an opportunity to grow and develop with us!

Program Requirements:

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Currently enrolled in an accredited college/university during program calendar year 2021

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Completed at least 2 years of college/university to be eligible for the program.

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Must have a ≥3.0 GPA. Please attach a copy of your transcript in order to be considered for this internship opportunity.

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Minimum availability of 12 weeks (Required start on or before program Welcome Reception and end date on or after Summer End Poser Symposium).

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Previous experience in the job duties listed, either through course work or industry/academia

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Participation in student organizations and/or other leadership experience

The Discovery Research Biomarker Technologies team at Roche Diagnostic RED will be conducting research projects during summer 2021. The projects will be aimed at testing an innovative immune receptor repertoire based assay in the area of cancer diagnostics or other diseases. It is expected that there will be opportunities for summer interns to learn about Roche's strategy in NGS diagnostics, while working on specific assay research tasks. Immune repertoire sequencing is a novel diagnostic tool with huge potential as it just sees its entry into the clinical diagnostic. Allowing to “read” the immune response enables new monitoring and detection possibilities driven by data and personalised health care.

Three areas of research will benefit from assigning specific work blocks to students:

1. TCR and BCR repertoire sequencing from representatively sampled tumor tissue material

2. Analyzing the generated data using inhouse analysis tools.

3. Optimization specific aspects of the assay and evaluating new analysis tools.

The project will have several areas of specific hypothesis testing, where summer interns will participate in design of experiments, executing laboratory experiments, including NGS, contribute to data analysis, and present results to RED teams and across RMS.

Qualifications:

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Major in molecular biology, genetics, biotechnology, biochemistry, microbiology, or similar.

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Completion of a four or five year college program.

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Principles and rationales of Next Generation Sequencing

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Ability to work independently in a molecular laboratory

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Detailed record keeping

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Knowledge about the immune system

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Data analysis and interpretation

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Basic bioinformatic capabilities

What you will learn:

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NGS assay design, wet lab experimental design, planning of experiments

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Learning advanced molecular biology laboratory skills.

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Sample preparation for NGS, including manipulation of tumor tissue, plasma, blood cells, cultured human cells etc. DNA, RNA extraction methods, QC methods.

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PCR, NGS library construction, operation of NGS instruments.

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Sequence data analysis.

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Sequence data interpretation, statistical methods in biology, including e.g. immune receptor sequence analysis

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Teamwork, collaboration, presentation skills

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Experience culture and environment of Roche, the leader in clinical molecular diagnostics

Given the current uncertainty of the global pandemic and work from home situation for 2021, the majority of internships are currently planned to be virtual with the option for interns to work remotely from within U.S. Borders. Internships that operate in business critical roles, such as Operations and Research & Development may require you to work on campus. We will keep candidates informed if this changes.

Roche is an equal opportunity employer and strictly prohibits unlawful discrimination based upon an individual's race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, mental/physical disability, medical condition, marital status, veteran status, or any other characteristic protected by law.

If you have a disability and need an accommodation in connection with the on-line application process, please email us at US.Accommodation@roche.com .

·  Who we are

At Roche, 98,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we've become one of the world's leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Roche is an equal opportunity employer and strictly prohibits unlawful discrimination based upon an individual's race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, mental/physical disability, medical condition, marital status, veteran status, or any other characteristic protected by law.