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Offers “Sanofi”

days ago Sanofi

Scientist (Postdoc)

  • Internship
  • Vitry-sur-Seine ( Val-de-Marne )
  • Personal services

Job description



Sanofi’s Immuno-Oncology Therapeutic Area based in Vitry-sur-Seine, France is seeking a highly qualified and motivated PhD level post-doctoral candidate with an interest in Natural Killer (NK) cell biology and cancer immunotherapy. The successful candidate will provide scientific leadership and play a pivotal role in advancing the understanding of NK cell regulatory mechanism and enable discovery of novel regulators of NK cell immune functions and anti-tumor activity. The candidate will have a unique opportunity to work and train in a multidisciplinary research environment and will work closely with different scientists in Immuno-Oncology, Precision Oncology and Translational Sciences. The candidate will also assume responsibility to complete leading edge research for presentation in scientific meetings and publication.

Key Tasks & Responsibilities:

· Lead research efforts in Sanofi’s Immuno-Oncology Therapeutic Area to understand NK cell regulatory receptors in cancer.
· Establish an in vitro screening to discover and characterize key regulatory receptor of NK cell immune functions and anti-tumor activity.
· Implement multiple state-of-the-art techniques in molecular and cellular biology to increase NK cell cytotoxicity against tumor cell lines.
· Maintain a working knowledge of current experimental techniques and literature in the field of NK cell biology and NK cell therapies.
· Analyze, interpret, and present experimental results at lab meetings and share scientific results with our multi-disciplinary research group.
· Publish/present findings in peer-reviewed journals/scientific conferences.
· Work well with colleagues in a matrixed, fast-paced pharmaceutical research environment.
· Maintain accurate records of experiments and analyses.
· Maintain lucid and effective communication with manager and other colleagues

Key Tasks & Responsibilities:

· Lead research efforts in Sanofi’s Immuno-Oncology Therapeutic Area to understand NK cell regulatory receptors in cancer.
· Establish an in vitro screening to discover and characterize key regulatory receptor of NK cell immune functions and anti-tumor activity.
· Implement multiple state-of-the-art techniques in molecular and cellular biology to increase NK cell cytotoxicity against tumor cell lines.
· Maintain a working knowledge of current experimental techniques and literature in the field of NK cell biology and NK cell therapies.
· Analyze, interpret, and present experimental results at lab meetings and share scientific results with our multi-disciplinary research group.
· Publish/present findings in peer-reviewed journals/scientific conferences.
· Work well with colleagues in a matrixed, fast-paced pharmaceutical research environment.
· Maintain accurate records of experiments and analyses.
· Maintain lucid and effective communication with manager and other colleagues

Basic Qualifications:

· PhD in Immunology or Immuno-Oncology with publications in internationally recognized journals in the area of NK cell biology. Expertise in NK cell biology, characterization and functional manipulation.
· Experience in cell culture, cell-based assays, co-culture systems, multicolor flow cytometry and FACS
· Excellent English speaking, reading and writing skills
· Strong analytical and organizational skills
· Curiosity and a willingness to work independently and in collaboration with internal and external partners.
· Excellent teamwork skills and flexibility

Preferred Qualifications:

· Expertise in NK cell functional screens implementation and analysis.
· Expertise in gene editing and/or gene expression will be appreciated.
· A first experience as a post-doc in Immuno-Oncology and/or NK cell biology is a plus (0-2 years of prior postdoctoral training).

Basic French speaking skills are preferred but not mandatory

At Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.

As part of its diversity commitment, Sanofi is welcoming and integrating people with disabilities.