Scientist / PostDoc (m/f/d) Plasmid Sciences at Penzberg Site

Job description

·  Job facts

Pharma Technical Development Europe Biologics brings game-changing therapies from clinical phase I into the market. We are striving for a caring and sensing network organization which lives a culture of trust and collaboration. Our smart people drive innovation through their expertise, passion and "can do" mentality with the benefit for the patient being in the centre of our thoughts and efforts. Our core business is to develop safe, innovative and effective drugs using cutting edge technologies for manufacturing processes, clinical supply, formulation, device, packaging, and analytical development. In addition to a longstanding expertise for monoclonal antibodies we are building up capabilities for in vivo gene therapy focussing on the following main tasks:

·  Technical Development and clinical supply of viral vectors for in vivo gene therapy indications
·  Technical Development and supply of Plasmid DNA as a key element and starting material for in vivo gene therapy modalities across the whole Roche network

We are looking for a highly motivated scientist or PostDoc for the development and implementation of cutting edge technologies to generate and characterize plasmid and minicircle DNA in order to advance therapeutic modalities to cure diseases with gene therapy.

Your specific role

The position comprises predominantly the following tasks:

·  Development of a state-of-the art plasmid manufacturing bioprocess including independent planning and execution of experiments as well as interpretation, evaluation and documentation of development data
·  Scientific evaluation, interpretation and implementation of emerging technologies for the generation and analytical characterization of plasmids
·  Driving the science together with a highly enthusiastic, agile and crossfunctional team interacting with development experts in Early Research, Bioprocess Development, Analytical Development and the Clinical Supply Center
·  Close collaboration and co-creation with key external vendors will be one of your key responsibilities
·  Supporting the transfer and implementation of new technologies into a GMP environment
·  Supply of plasmids for R&D activities for the whole Roche network
·  Coach and support junior staff in the team

Who we are

Die Roche Diagnostics GmbH (RDG) ist mit mehr als 12.000 Mitarbeitern der drittgrößte Standort im Konzern. Neben den Vertriebsorganisationen in Deutschland (Roche Pharma AG und Roche Diagnostics Deutschland) fokussiert die RDG auf das operative Geschäft. In den beiden Standorten Mannheim und Penzberg werden neue diagnostische Tests und pharmazeutische Wirkstoffe für den weltweiten Markt entwickelt und produziert.

Roche ist ein Arbeitgeber, der die Chancengleichheit fördert.

Desired profile

Who you are

You're someone who wants to influence your own development. You're looking for a company where you have the opportunity to pursue your interests across functions and geographies. Where a job title is not considered the final definition of who you are, but the starting point.

For this interesting challenge, you bring the following qualification:

·  An Engineer/Master degree and ideally a PhD in life sciences or alternatively long standing relevant industry experience
·  Expertise and hands-on experience in the bioprocess development of E.coli fermentation and purification technologies for biomolecules are key skills, additional experience with disposable technologies would be a plus
·  Profound knowledge and working experience with traditional plasmid and/or minicircle DNA and molecular biology
·  Hands-on experience in molecular biology and analytical methodologies like Next Generation Sequencing (NGS) would enrich your profile
·  A strong team player but capable of working independently with the ability to explore and implement own individual ideas
·  Excellent problem-solving skills with a strong drive and high degree of self motivation

Please contact us if you have any questions!

We are pleased that you are considering Roche as a potential employer! Our FAQ will help you with various questions regarding the application process.

With people. For people.

Do you need further assistance? Our Talent Acquisition Team is available for you by phone from monday to friday from 9-12 am and from 1-4 pm by phone: (+49) (0) 621-759 68642. We are pleased to respond to your inquiries.

Roche is an equal opportunity employer.

This position is a full-time position limited to three years.

Roche ist ein Arbeitgeber, bei dem Chancengleichheit zählt.
Technical Development, Technical Development > Technical R&D

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