Roche Postdoctoral Fellowship (RPF) – Agonistic antibodies (from March, 24 months)

Job description

·  Job facts

Who we are (Global):

At Roche, over 90,000 people across 150 countries are pushing back the frontiers of healthcare. Working together, we've become one of the world's leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity, and on seeing each other's differences as an advantage. To innovate healthcare, Roche has ambitious plans to keep learning and growing – and is seeking people who have the same goals for themselves.

At Roche, we believe it's urgent to deliver medical solutions right now – even as we develop innovations for the future. We are passionate about transforming patients' lives and we are fearless in both decision and action. And we believe that good business means a better world.

That is why we come to work every single day. We commit ourselves to scientific rigour, unassailable ethics, and access to medical innovations for all. We do this today to build a better tomorrow.

The Position

As postdoctoral fellow in the Large Molecules Research (LMR) department located in Schlieren (Zurich), Switzerland, you will be driving a project that addresses the generation of antibodies that should induce agonistic activity on defined immune-receptors.

The aim of this project is to evaluate different routes and methodologies for the targeted delivery and assembly of immune activating compounds.

You will:

·  Generate the tools and antigens for the antibody generation campaigns against those receptors.
·  Perform in vitro display antibody selection.
·  Characterize the antibodies in vitro by SPR and FACS.
·  Characterize the putative therapeutic molecules in cellular activity assays.
·  Organize and pursue the interactions between all partners involved.
·  Present data at internal and external meetings.

This position is sponsored by the Roche Postdoctoral Fellowship Program (RPF) and is initially set for two years, extension for a third year is possible.

Who we are

Das Roche Innovation Center Zürich (Roche Glycart AG) ist in der Erforschung und Entwicklung gentechnischer therapeutischer Antikörper tätig. Schwerpunkte sind die Krebs-Immuntherapie sowie die Immuntherapie allgemein. Glycart gehört seit 2005 zur Roche-Gruppe und beschäftigt zirka 140 Mitarbeitende. Mehr dazu .

Roche ist ein Arbeitgeber, der die Chancengleichheit fördert.

Desired profile

Who you are

You are someone who wants to influence your own development. You are flexible, proactive, creative and detail-oriented, and have top teamwork competency but can also work highly independent.

You fit those requirements:

·  A recent PhD in biochemistry/biotechnology (max 3 years after completing PhD)
·  Extensive practical knowledge in molecular biology, with some focus on phage display or related in vitro display technologies.
·  High competency and technical affinity to maintain sophisticated lab equipment.
·  Prior experience in cell based biological assays.
·  Proven ability to present and publish research data.
·  Excellent inter-personal and communication skills / ability to build good working relations.
·  Proficiency in spoken and written English. German language is a plus.

The anticipated start date of this fellowship is 1st March 2020. Please clearly indicate your preferred starting date on your motivation letter. All applications always need to include a CV, motivation letter and a certificate of your PhD (if already available).

Do you know what Roche stands for? Roche embraces diversity and equal opportunity in a serious way. We are committed to building a team that represents a variety of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be.

If you still have questions, then please check our FAQs and videos on careers.roche.ch/faq

Tags: ROiQQ ROiLS ROiBT ROiCH ROiEE ROiBING ROiCE RPF

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