Master thesis - Synthesize and application testing

Job description

3374688
Additional Cities

Uppsala
Career Level

Co-op/Intern
Relocation Assistance

No
Business

GE Healthcare
Business Segment

Healthcare BioPharma
Function

Engineering/Technology
Country/Territory

Sweden
Postal Code

751 84
Role Summary/Purpose

Master thesis - Synthesize and application testing of alternative molecular weight marker used in gel filtration

GE Healthcare Life Sciences provides products and services used as tools for biopharmaceutical manufacturing, drug discovery and the latest in cellular technologies, thereby enabling our customers around the world to be more productive, effective and innovative.
Essential Responsibilities

GE Healthcare Life Sciences work with a wide range of products for both lab- and bioprocess scale. The product portfolio for the Resins department ranges from sample preparation kits to resins and pre- packed columns for purification of biomolecules. These columns must be thoroughly quality tested before reaching the customers to assure product quality. The customers regularly also test the optimal performance of their columns by using calibrations kits and markers.

New alternatives to current markers used for gel filtration techniques are needed. These markers are used as molecular weight markers for calibration curves both externally by costumers and internally as a QC standard. In addition, markers of void volumes are used in certain methods and in QC release of gel filtration columns.

This master thesis work includes investigation of alternative products suitable for defining gel filtration column properties. More specifically, evaluate available and/or synthesize novel markers of column void volumes and investigate their performance in comparison currently used marker(s). Techniques used in this work will be organic chemistry, gel filtration and other chromatography techniques.

Master thesis work will be for spring 2020. Deadline for application is 15th November 2019. For questions, please contact Anna Jansson: anna.jansson@ge.com or Nils Norrman: nils.norrman@ge.com.
Qualifications/Requirements

The project requires experience in organic chemistry, interest and enthusiasm for application/analytical chemistry and a systematic and analytic mindset. GE Healthcare contributes with outstanding supervision and world-class instrumentation.
About Us

GE (NYSE:GE) drives the world forward by tackling its biggest challenges. By combining world-class engineering with software and analytics, GE helps the world work more efficiently, reliably, and safely. GE people are global, diverse and dedicated, operating with the highest integrity and passion to fulfill GE’s mission and deliver for our customers. www.ge.com

GE Healthcare provides transformational medical technologies and services to meet the demand for increased access, enhanced quality and more affordable healthcare around the world. GE works on things that matter - great people and technologies taking on tough challenges. From medical imaging, software & IT, patient monitoring and diagnostics to drug discovery, biopharmaceutical manufacturing technologies and performance improvement solutions, GE Healthcare helps medical professionals deliver great healthcare to their patients. Learn More About GE Healthcare .

GE is committed to taking on the world’s toughest challenges. In order to fulfill that promise we rely on a culture of leadership, diversity and inclusiveness. We aim to employ the world’s brightest minds to help us create a limitless source of ideas and opportunities. We believe in hiring talented people of varied backgrounds, experiences and styles…people like you!

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Primary Country

Sweden
Primary State/Province

Uppsala
Primary City

Uppsala